Clinical Pathology Laboratory - Reference Intervals
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Immunology Reference Intervals
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| We have established reference intervals for agarose gel electrophoresis
and for immunoglobulin values in dogs and cats using the equipment
and reagents in our laboratory. Other reference intervals provided
with our reports have been provided by the manufacturer of the kits
we use for these tests. |
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Agarose Gel Reference Intervals |
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| These reference intervals were established using our Helena-REP
agarose gel electrophoresis equipment. |
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Test
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Units
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Canine
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Feline
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Equine
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Bovine
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Albumin
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g/dL
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2.2 - 3.3
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2.4 - 3.8
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2.3 - 3.5
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2.6 - 3.9
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Total a1
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g/dL
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0.1 - 0.3
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0.5 - 1.2
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0.3 - 0.8
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0.3 - 0.5
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Total a2
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g/dL
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1.0 - 1.6
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0.8 - 1.4
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0.7 - 1.3
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0.8 - 1.3
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Total a
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g/dL
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1.1 - 1.8
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1.5 - 2.3
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1.2 - 1.7
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1.2 - 1.6
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Total b1
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g/dL
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0.3 - 1.0
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0.3 - 0.7
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0.2 - 1.1
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0.6 - 1.0
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Total b2
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g/dL
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0.2 - 1.0
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0.1 - 0.6
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0.3 - 0.8
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0.5 - 0.9
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Total b
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g/dL
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0.8 - 1.8
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0.5 - 1.2
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0.7 - 1.6
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1.2 - 1.8
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g
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g/dL
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0.3 - 1.1
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0.6 - 2.1
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0.7 - 1.8
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1.1 - 2.7
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Total globulin
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g/dL
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2.6 - 4.2
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3.4 - 5.1
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2.8 - 4.7
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3.8 - 5.7
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A:G
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.
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0.5 - 1.1
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0.5 - 1.2
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0.6 - 1.1
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0.5 - 1.0
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Immunoglobulin Reference Intervals |
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| These reference intervals were established in our laboratory using
radial immunodiffusion kits obtained from Bethyl laboratories. Because
kits from different manufacturers do not provide identical results
(due to the use of different standards), our results cannot be directly
compared to that from other laboratories. These ranges are only valid
for dogs and cats > 1 year of age. Animals younger than this may
very well have values below the reference intervals.
Please note that for canine IgA, when the reference interval was
established, the lowest IgA standard provided by the kit was 35
mg/dL. Therefore, the lowest reportable value for IgA was 35 mg/dL.
The lowest IgA standard with the kit has now changed to 33 mg/dL.
Therefore, when we report IgA values of 33 mg/dL, they should be
regarded as being equivalent to 35 mg/dL and are not compatible
with IgA deficiency.
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Test
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Units
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Canine
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Feline
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IgG
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mg/dL
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670 - 1650
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530 - 2000
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IgM
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mg/dL
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100 - 400
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75 - 260
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IgA
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mg/dL
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35 -270
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25 - 200
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