
Aspirate from an abdominal mass associated with the intestine in
an old cat. The mass is composed of large numbers of lymphoid cells
with bright red intracytoplasmic granules with a clear halo. The
granules are readily visualized in the cells highlighted by the
red arrows. The results are compatible with a lymphoma of granular
lymphocytes. This is a particular type of lymphoma that usually
arises in the ileum and readily metastasizes to mesenteric lymph
nodes, liver and spleen. This type of lymphoma is either of cytotoxic
T cell or natural killer cell origin and is poorly responsive to
standard lymphoma chemotherapeutic protocols.